langerhans cell histiocytosis in childhood: review, symptoms in the oral cavity, differential diagnosis and report of one case

نویسندگان

mohammad shooriabi assistant professor, department of oral medicine, school of dentistry , ahvaz jundishapur university of medical sciences, ahvaz, iran

mohsen parsazade pathologist of imam khomeini hospital, ahvaz jundishapur university of medical sciences, ahvaz, iran

shahram bagheri pathologist of shafa hospital, ahvaz jundishapur university of medical sciences, ahvaz, iran.

seyed amir razavi satvati assistant professor, department of endodontics, school of dentistry, north khorasan university of medical sciences, bojnurd, iran

چکیده

background langerhans cell histiocytosis (lch) is a rare disease in which monoclonal migration and proliferation of specific dendritic cells is seen. the disease primarily affects the bones and skin, but there is a possibility that involves other organs or appears as a multi-systemic disease. case report in oral examination of a nine-month girl, two deep wounds with a yellow membrane with approximate size of 1 × 1 cm on both sides of mandibular alveolar ridge were seen. the edges of the wounds were swollen and proliferated and redder than the surrounding mucosa. at the touch the edges of the wound were not indurated. the wound were created from the third-month and the size of wounds had become slightly larger within 6 months. according to the chronic wound and being non-responsive to various systemic and local treatments, incisional biopsy was taken from the wounds. langerhans cell histiocytosis was confirmedhistologically and immune histochemically. conclusion mouth ulcers may be the only symptoms of langerhans cell histiocytosis. therefore, the role of dentist could be important in diagnosis of this disease.

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Langerhans Cell Histiocytosis in Childhood: Review, Symptoms in the Oral Cavity, Differential Diagnosis and Report of One Case

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عنوان ژورنال:
international journal of pediatrics

جلد ۴، شماره ۸، صفحات ۳۳۴۳-۳۳۵۳

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